Help solve either of these tricky medical cases and win up to $350,000 in prizes!
We hope you’ll participate. By doing so, you’ll have the potential to win a six-figure reward, pioneer a breakthrough, and quite literally change two lives.
On this site, you can access fully de-identified case files of Patient A and Patient B (two real patients who are substantially suffering and who have gone undiagnosed and without effective treatments despite substantial efforts). Every idea you submit is first reviewed by the patients’ prescribing physician to ensure clinical safety, legal compliance, and HIPAA-integrity—so you know your insight reaches the right hands. Crack their diagnosis or find a treatment that works for them, and you’ll earn a large cash prize, public acknowledgment (if you choose to accept it), and the satisfaction of turning serious suffering into a recovery story.
Whether you’re a doctor, scientist, data sleuth, or just love a medical mystery, we’d be grateful if you’d take part. Doing so is simple - just email us (medicalsolutionbounty@gmail.com) your idea for a diagnosis, treatment, or test to conduct, along with a convincing, well-reasoned rationale for why you’re proposing it. You can win if you crack either patient’s mystery or propose a treatment that’s effective!
Patient A
Patient A is experiencing:
Progressive muscle weakness and atrophy (started ~10 years ago)
Significant balance issues and mobility decline
Recent arm weakness (sudden onset right arm June 2024, now bilateral)
Peripheral sensory disturbances (numbness, pins/needles in feet/legs; prickly sensation)
Diagnosed with CIDP but did not respond to IVIG treatment
History of monoclonal gammopathy (IgG-kappa MGUS)
Recent pulmonary embolism (June 2024)
Despite extensive testing and multiple specialist consultations at top medical centers, the condition continues to worsen without a definitive diagnosis or effective treatment. Full information about Patient A’s case can be found here.
Patient A Reward Structure
Grand Prize: $250,000
Awarded to a submission that leads to a cure or an effective treatment for the condition.
Best Submission Prize: $50,000
Awarded to the most promising submission that doesn't win the grand prize. This prize will be awarded regardless of whether any submission leads to effective treatment or a diagnosis, so long as at least 50 total submissions are received.
Useful Information Prizes: Up to five at $2,000 each
Awarded to five different individuals who provide especially helpful submissions that result in any of the following:
A new treatment being attempted
A new test being conducted
A new diagnosis pathway being explored
These useful information prizes will be awarded even if the information ultimately doesn't lead to resolution of the condition.
Patient B
Patient B is experiencing:
Constant dull diffuse “burning” sensation, a few inches above the belly button, present 100% of waking time.
Nausea that fluctuates throughout the day, varying from not at all present to fairly intense.
Despite extensive testing and multiple specialist consultations, no treatments that help significantly have been identified. Full information about Patient B’s case can be found here.
Patient B Reward Structure
Grand Prize: $100,000
Awarded to a submission that leads to a cure or an effective treatment for the condition.
Best Submission Prize: $20,000
Awarded to the most promising submission that doesn't win the grand prize. This prize will be awarded regardless of whether any submission leads to effective treatment, so long as at least 50 total submissions are received.
Useful Information Prizes: Up to five at $1,000 each
Awarded to five different individuals who provide especially helpful submissions that result in:
A new treatment being attempted
A new test being conducted
A new diagnosis pathway being explored
These useful information prizes will be awarded even if the information ultimately doesn't lead to resolution of the condition.
Submission Process
To participate in this bounty, please send your submission of a proposed treatment, test, diagnosis, or other helpful suggestion to medicalsolutionbounty@gmail.com. Please include a well-reasoned rationale for any recommendations being made. You will receive an email if your submission has been chosen as a prize winner.
All submissions are routed to the prescribing physician for initial clinical review. Patient privacy is paramount, and all identifying information has been removed from records.
By entering you agree to the Official Rules.